For those passionate about cellular health, longevity, and the intersection of science with beauty, Renue by Science offers a compelling story—from pioneering supplements to breakthrough skincare.
1. Who They Are
Founded by Bryan Nettles, Renue by Science positions itself as a forward-thinking brand committed to “advancing longevity science” by making cutting-edge research available to consumers worldwide PR NewswireRenue By Science. The team includes experts like Dr. Rebecca Crews (Research Director), Dr. Clark Driggers (Chief Medical Advisor), and Monica North (New Product Development), ensuring deep scientific grounding Renue By Science.

2. The Innovation in Supplements
Originally known for NAD⁺ precursor supplements—like NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside)—their hallmark lies in using liposomal (or nanoliposome) delivery systems to enhance absorption and bioavailability.
3. Stepping Into Skincare with Renue Blue™
In January 2025, they launched Renue Blue™, a skincare line designed to support skin longevity using topical NAD⁺ delivery. Active ingredients include:
- NAD+ complex (NAD⁺, NMN, NR)
- Methylene Blue (novel antioxidant)
- Resveratrol, Apocynin
- Glutathione, Hyaluronic Acid, ALA in face and body formulations
The true differentiator? Liposomal technology—nano-sized vesicles that deliver actives past the skin barrier for deep, targeted rejuvenation. This combination creates a dual-action effect: nourishing deep skin layers while fortifying surface protection Renue By Science.

Around the world, customers report smoother skin, faded sun spots, improved elasticity, and faster absorption using Renue protocols—though these are anecdotal testimonials Renue By Science .
4. Community Buzz: Praise & Constructive Criticism
- Positive feedback: “Look at the vendor rankings… Consensus is renue by science and donotage”.
Others cite reliable customer support:
“They re‑shipped… in 2 days… seamless… Renue rocks”.
Additionally, one user praised overall value of Renue for NMN sourcing and quality:
“For value the go to is always Renue by Science”. - Skepticism:
Some users caution over bioavailability claims. A Redditor questioned Renue’s “10x bioavailability” promise in their liposomal products: “Raises serious questions… absence of a key study… if it is not really 10x bioavailable…”
Another raised concerns over purity levels in lab testing:
“Renue by Science had the lowest purity amongst the three at 82.6%… totally unacceptable… I’d be demanding an explanation”
Additionally, one buyer noted Amazon listing inconsistencies where a bottle listed as 120 capsules actually contained only 90.
5. Why You Might Be Intrigued
- Science-led formulations anchored in NAD⁺ research
- Liposome delivery tech designed for enhanced bioactivity
- Expanding into skincare, offering deep cellular nourishment for longevity-focused consumers
- Generally positive customer service and evolving presence in longevity communities
- At the same time, healthy skepticism remains—they’re responsive brand-wise—but claims should be evaluated critically and backed by peer-reviewed evidence.
In Summary
Renue by Science stands at the crossroads of wellness, longevity, and cosmetic innovation. From supplements that aim to optimize cellular energy production to skincare lines built on NAD⁺ delivery breakthroughs, their mission to blend research, accessibility, and performance is clear.
However, as with any supplement or advanced skincare, especially from emerging companies, doing your own due diligence—examining third-party test results, studying scientific citations, and reviewing user experiences—is essential.