Renue by Science has carved a niche in the wellness and longevity space through its focus on NAD⁺ precursors and liposomal delivery systems. Let’s explore their key offerings, what sets them apart, and how they stack up.
1. Flagship Products & Delivery Forms
LIPO NR Capsules
- What it is: Liposomal Nicotinamide Riboside in capsule form (300mg per serving). Designed for improved absorption and a slower release into the bloodstream.
- Why it matters: Independent analysis lists this as the “best safety profile” and greatest value among NR supplements, especially due to its modest dose and efficient liposomal delivery.

NR Powder (NR‑1000)
- Form: High-strength, non-liposomal NR powder—offering flexibility in dosing.
- Cost-efficiency: Remarkably cost-effective, albeit with potentially lower bioavailability compared to liposomal versions.
LIPO NMN & Pure NMN Powder
- LIPO NMN: Liposomal NMN (capsule or powder) aims for enhanced delivery and protection through digestion.
- Pure NMN Powder: A simple, sublingual crystalline form offering customizable dosing and affordability.
LIPO NAD⁺ Complete
- A powerful 4-in-1 formulation combining NAD⁺, NMN, NR, and Trigonelline in liposomal form for comprehensive NAD+ support.
- Consumer note: Some users have reported discrepancies between the website’s ingredient claims and actual bottle labeling, raising consistency concerns.
Serums and Other Forms
- NAD Defender / Body Serum: Topical formulations delivering NAD⁺ complex with antioxidants like glutathione and vitamin D3 for skin and surface nourishment.
- Renue also offers nasal sprays and gels, designed for faster absorption or targeted delivery.
2. Liposomal Technology: Claims vs. Consumer Feedback
Renue’s liposomal (CellG8) system is a key selling point—promising superior bioavailability. The brand claims up to 10× better absorption using liposomal delivery.
However, discussions on Reddit and independent reviews add nuance:
“My experience… raises serious questions about the validity of these claims, particularly the ’10x bioavailability’ claim.”

Another user notes concerns about product purity:
“Renue by Science had the lowest purity amongst the three at 82.6%… totally unacceptable.”
These perspectives suggest that while liposomal delivery promises clear advantages, claims should be viewed critically—and backed by transparent third-party testing.
3. Scientific Backing & Brand Transparency
- Research highlights: A study cited by Renue suggests that liposomal NMN boosted NAD+ levels by ~83% in 4 weeks—a compelling indicator of effectiveness. Renue By Science
- Safety and testing: Renue products are reportedly tested in ISO- and cGMP-certified labs, are non-GMO, and avoid artificial preservatives—factors that support product confidence.
4. Community Voices—The Good & the Cautious
Positive experiences:
- Many users report noticeable increases in energy, improved recovery, and even enhanced skin and hair health after using sublingual NMN or fisetin supplements.
Concerns:
- Delivery delays, especially for LIPO NAD⁺ Complete, may disrupt regimens and affect consistency.
- As mentioned previously, issues around purity levels and liposomal efficacy have spurred on cautious discussion.
5. Who Might Benefit from Renue by Science?
Key Factor | Ideal For… |
---|---|
Bioavailability Boost | Those seeking enhanced absorption via liposomes |
Dosing Flexibility | Users wanting capsules, powders, serums, or sprays |
Comprehensive NAD Support | People aiming for both NMN and NR combined |
Willingness to Research | Users who verify claims and read reviews |
Final Thoughts
Renue by Science offers a diverse, science-driven product lineup—from liposomal NAD+ boosters to topical serums—all backed by sophisticated delivery methods and industry-standard testing.
However, as with any supplement, it pays to look beyond marketing:
- Scrutinize bioavailability claims and seek evidence or third-party validation.
- Monitor consistency in product formulation and fulfillment, especially if you rely on daily dosing.
- Listen to user feedback—both positive and critical—to get a rounded perspective.